| Family | Family classification from SLC1 to SLC52 |
| Faimly | Family classification from SLC1 to SLC52 |
| SLC name | The name of SLC gene is expressed in the format SLCnXm (n, a family number; X, an alphabet representing a subfamily; m, a number assigned to individual gene) |
| Isoform | Identifier, named by the number or alphabet, with different mRNA produced from the same locus |
| Protein name | Standardized nomenclature of the protein described in SLC Tables |
| Alias | Another name of the protein |
| Family description | Summary of the SLC family described in SLC Tables |
| Family | Family classification from SLC1 to SLC52 |
| Transport type | A type of transporting mechanism |
| Coupling ion | Coupled ion type. Valid only when 'transport type' is co-transporter. |
| SLC name | The name of SLC gene is expressed in the format SLCnXm (n, a family number; X, an alphabet representing a subfamily; m, a number assigned to individual gene) |
| Isoform | Identifier, named by the number or alphabet, with different mRNA produced from the same locus |
| Ligand name | Known ligand |
| Transport type | A type of transporting mechanism |
| Coupling | Coupled ion type. Valid only when 'transport type' is co-transporter. |
| E-value | E-value obtained from sequence similarity search by FASTA36 |
| SLC name | The name of SLC gene is expressed in the format SLCnXm (n, a family number; X, an alphabet representing a subfamily; m, a number assigned to individual gene). If the SLC has splice variants, SLC gene is named in the form SLCnXmpl, where p is for an alphabet representing a splice variant, l is for a digit or alphabet assigned to each variant. |
| Hierarchical Edge Bundling | Visualized result of FASTA36 on the threshold set by E-value |
| Family | Family classification from SLC1 to SLC52 |
| SLC name | The name of SLC gene is expressed in the format SLCnXm (n, a family number; X, an alphabet representing a subfamily; m, a number assigned to individual gene). If the SLC has splice variants, SLC gene is named in the form SLCnXmpl, where p is for an alphabet representing a splice variant, l is for a digit or alphabet assigned to each variant. |
| Heatmap | All-against-all sequence identities among the protein in the same family visualized by heatmap |
| Clustering | Hierarchical clustering depicted in a dendrogram |
| Family | Family classification from SLC1 to SLC52 |
| The length of Amino acid sequence | Amino acid sequence length from 1 to 700 per 100 |
| SLC name | The name of SLC gene is expressed in the format SLCnXm (n, a family number; X, an alphabet representing a subfamily; m, a number assigned to individual gene). |
| Isoform | Identifier, named by the number or alphabet, with different mRNA produced from the same locus |
| Locus | Position of the gene on a chromosome |
| RNA accession | Accession number of the RNA sequence |
| RNA length | RNA sequence length |
| AA accession | Accession number of the amino acid sequence |
| AA length | Protein sequence length |
| AA name | The name of the protein |
| Family | Family classification from SLC1 to SLC52 |
| Multiple sequence alignment | Amino acid sequence alignment produced by MAFFT |
| Conservation | Asterisk(*) represents 100% conserved position, colon(:) represents >80% conserved position, period(.) represents >50% conserved position |
| Mutation site | Mutation sites are shown by background colors; pink(Pathogenic), cyan(Benign) and grey(Unknown). |
| Family | Family classification from SLC1 to SLC52 |
| Resolution | Resolution of the structure determined by X-ray crystallography |
| Experiment | Method of determining three-dimensional structure of the protein |
| Species | Organism from which the protein was characterized |
| E-value | The range of E-values of the sequence against the protein sequence in PDB |
| SLC name | The name of SLC gene is expressed in the format SLCnXm (n, a family number; X, an alphabet representing a subfamily; m, a number assigned to individual gene). |
| Isoform | Identifier, named by the number or alphabet, with different mRNA but produced from same locus |
| PDB ID | ID in PDB |
| Chain | chain ID in the PDB file |
| E-value | E-value of the sequence against the protein sequence in PDB |
| Identity | Sequence identity |
| Positive freq. | Positive matching (positive-scoring in BLOSOM62) ratio in the sequence alignment |
| Gap freq. | Gap ratio in the sequence alignment |
| Coverage | Ratio of the hit protein length to the query protein length |
| Species | Organism from which the protein was characterized |
| Resolution | Resolution of the structure determined by X-ray crystallography |
| Experiment | Method of determining three-dimensional structure of the protein |
| SLC transporter | The name of SLC gene is expressed in the format SLCnXm (n, a family number; X, an alphabet representing a subfamily; m, a number assigned to individual gene). If the SLC has splice variants, SLC gene is named in the form SLCnXmpl, where p is for an alphabet representing a splice variant, l is for a digit or alphabet assigned to each variant. |
| Coverage | The detail results of BLAST search of each SLC protein for PDB. The red box on the top represents query sequence. Boxes in blue stripe represents a sequence in PDB similar to the query. The blue stripe has four different color modes which represent the degree of matches between query sequence and the protein sequence in PDB. |
| Family | Family classification from SLC1 to SLC52 |
| Region | Topology region: R1, extracellular region; R2, border between outside and transmembrane region (±2 AA); R3, transmembrane region; R4, border between transmembrane region and cytosole (±2 AA); R5, cytosolic region . |
| Clinical significance | Clinical significance described in ClinVar |
| SLC name | The name of SLC gene is expressed in the format SLCnXm (n, a family number; X, an alphabet representing a subfamily; m, a number assigned to individual gene). |
| Type | Type of the variation; substitution, frame shift, deletion, duplication and synonymous substitution. |
| Significance | Clinical significance described in ClinVar |
| Criteria | Status of the review of the variant |
| Disease | Relating diseases descrived in ClinVar |
| Seq start | Nucleotide number where the mutation starts |
| Seq end | Nucleotide number where the mutation ends |
| Seq original | Reference nucleotide |
| Seq new | Substituted nucleotide by the variant |
| AA start | Amino acid number where the mutation starts |
| AA end | Amino acid number where the mutation ends |
| AA original | Reference residue |
| AA new | Substituted amino acid residue in the variant |
| Var ID | A unique identifier for the set of sequence changes defined in ClinVar |
| Allele ID | A ClinVar identifier for each change |
| Chr | Chromosome number on which the variant is found |
| Loc | Location of the mutation on the chromosome |
| Assmbl | Genome assembly number |
| Family | Family classification from SLC1 to SLC52 |
| Mutation type | Type of the variation; missense, synonymous, frame shift, deletion, insertion, and nonsense.Type of the variation; missense, synonymous, frame shift, deletion, insertion, and nonsense. |
| Clinical significance | Clinical significance described in ClinVar |
| Criteria | Status of the review on the variant |
| SLC name | The name of SLC gene is expressed in the format SLCnXm (n, a family number; X, an alphabet representing a subfamily; m, a number assigned to individual gene). |
| Type | Type of the variation; substitution, frame shift, deletion, duplication and synonymous substitution. |
| Significance | Clinical significance described in ClinVar |
| Criteria | Status of the review of the variant |
| Disease | Related diseases described in ClinVar |
| Seq start | Nucleotide number where the mutation starts |
| Seq end | Nucleotide number where the mutation ends |
| Seq original | Reference nucleotide |
| Seq new | Substituted nucleotide by the variant |
| AA start | Amino acid number where the mutation starts |
| AA end | Amino acid number where the mutation ends |
| AA original | Reference residue |
| AA new | Substituted amino acid residue in the variant |
| Var ID | A unique identifier for the set of sequence changes defined in ClinVar |
| Allele ID | A ClinVar identifier for each change |
| Chr | Chromosome number on which the variant is found |
| Loc | Location of the mutation on the chromosome |
| Assmbl | Genome assembly number |
| Family | Family name with known 3D structure (PDB ID) |
| Mapping | Mutation sites are shown by pink sphere (pathogenic mutation), cyan sphere (benign mutation), and white sphere (unknown significance). The ribbon of the protein in target is gray-scaled based on the amino acid type conservation. |