iMusta4SLC

The membrane was genereated by OPM.
Red: extracellular (out) side,
Blue: cytoplasmic (in) side

Spacefill: the residues in concern.
pink: pathgenic
cyan: benign
white: uncertain

Ribbon colouring:
Grey: subunit in concern
(darker residue:conserved,
lighter residue:not conserved)
Shellwhite: other subunits

Mapping

SLC5 family: Known whole variation data

Mouse-overlay on the protein above may identify the AA # and type.

AA # in 3D above	AA type in 3D above	Original AA type	Mutated AA type
4	D	D	G
4	D	D	N
10	I	I	T
23	S	D	G
40	A	G	E
51	Y	A	T
60	Y	F	L
62	W	I	V
63	M	G	R
78	I	P	S
92	E	R	H
94	R	R	H
151	I	V	M
193	K	G	E
196	D	T	I
231	L	L	V
242	Q	Q	E
281	I	L	V
286	Q	I	T
313	V	N	D
314	G	G	A
319	V	M	T
330	S	T	P
344	M	R	Q
348	K	A	T
371	A	I	V
372	L	G	R
374	I	V	A
375	A	A	V
400	S	G	R
415	K	R	G
420	G	G	D
420	G	G	R
422	I	V	M
444	F	T	M
457	V	V	M
460	A	F	V
466	T	G	E
505	T	R	H
515	I	I	T
521	G	G	R
525	G	H	Q

AA # in 3D above	AA type in 3D above	Original AA type	Mutated AA type
4	D	D	G
4	D	D	N
10	I	I	T
23	S	D	G
40	A	G	E
51	Y	A	T
60	Y	F	L
62	W	I	V
63	M	G	R
78	I	P	S
92	E	R	H
94	R	R	H
151	I	V	M
193	K	G	E
196	D	T	I
231	L	L	V
242	Q	Q	E
281	I	L	V
286	Q	I	T
313	V	N	D
314	G	G	A
319	V	M	T
330	S	T	P
344	M	R	Q
348	K	A	T
371	A	I	V
372	L	G	R
374	I	V	A
375	A	A	V
400	S	G	R
415	K	R	G
420	G	G	D
420	G	G	R
422	I	V	M
444	F	T	M
457	V	V	M
460	A	F	V
466	T	G	E
505	T	R	H
515	I	I	T
521	G	G	R
525	G	H	Q

AA # in 3D above	AA type in 3D above	Original AA type	Mutated AA type
4	D	D	G
4	D	D	N
10	I	I	T
23	S	D	G
40	A	G	E
51	Y	A	T
60	Y	F	L
62	W	I	V
63	M	G	R
78	I	P	S
92	E	R	H
94	R	R	H
151	I	V	M
193	K	G	E
196	D	T	I
231	L	L	V
242	Q	Q	E
281	I	L	V
286	Q	I	T
313	V	N	D
314	G	G	A
319	V	M	T
330	S	T	P
344	M	R	Q
348	K	A	T
371	A	I	V
372	L	G	R
374	I	V	A
375	A	A	V
400	S	G	R
415	K	R	G
420	G	G	D
420	G	G	R
422	I	V	M
444	F	T	M
457	V	V	M
460	A	F	V
466	T	G	E
505	T	R	H
515	I	I	T
521	G	G	R
525	G	H	Q

AA # in 3D above	AA type in 3D above	Original AA type	Mutated AA type
4	D	D	G
4	D	D	N
10	I	I	T
23	S	D	G
40	A	G	E
51	Y	A	T
60	Y	F	L
62	W	I	V
63	M	G	R
78	I	P	S
92	E	R	H
94	R	R	H
151	I	V	M
193	K	G	E
196	D	T	I
231	L	L	V
242	Q	Q	E
281	I	L	V
286	Q	I	T
313	V	N	D
314	G	G	A
319	V	M	T
330	S	T	P
344	M	R	Q
348	K	A	T
371	A	I	V
372	L	G	R
374	I	V	A
375	A	A	V
400	S	G	R
415	K	R	G
420	G	G	D
420	G	G	R
422	I	V	M
444	F	T	M
457	V	V	M
460	A	F	V
466	T	G	E
505	T	R	H
515	I	I	T
521	G	G	R
525	G	H	Q